Symposia/Workshop programme

Endothelial aging: molecular mechanisms and functional significance

Synopsis

Organised by

Margaret D Brown (University of Birmingham, UK) and Richard CM Siow (King’s College London, UK)

Location *

TBC

0845	Welcome and Introduction Margaret D Brown & Richard Siow
0900	Jorge Erusalimsky ( Cardiff School of Health Sciences, UK) Mechanisms of endothelial cell senescence
0930	Bernd van der Loo (University Hospital Zurich, Switzerland) Signaling processes in endothelial aging in relation to chronic oxidative stress and their potential therapeutic implications
1000	Michael D Delp ( University of Florida, USA) Aging, exercise training and the endothelium in skeletal muscle arterioles
1030	Coffee
1100	Phillip Gates ( Peninsula Medical School, Exeter, UK) Human endothelial function and vascular aging in macro- and micro-vessels
1130	Stefano Taddei ( University of Pisa, Italy) The aging endothelium, cardiovascular risk and disease

Synopsis

In light of an aging population and the prevalence of cardiovascular disease today, the symposium will explore the role of vascular endothelial dysfunction in this scenario. It will focus on cellular mechanisms of endothelial senescence and pathways involved in oxidative stress-associated endothelial aging, linking these to structural and functional impairment of microcirculation in two key organ systems, skeletal muscle and skin, and the wider vascular health implications from a clinical perspective.

Symposia Location Key

LT 1	Babbage Lecture Theatre	(New Museums Site)
LT 2	Cockcroft Lecture Theatre	(New Museums Site)
LT 3	Main Physiology Lecture Theatre	(Downing Site)
LT 4	Main Anatomy Lecture Theatre	(Downing Site)
LT 5	Biffin Lecture Theatre	(Downing Site)
LT 6	Physiology Lecture Theatre 3	(Downing Site)
LT 7	Arts School Room B	(New Museums Site)
LT 8	Arts School Room C	(New Museums Site)